MolNFT v1 · #63270 · protein

Crystal structure of TIPE2

3F4M · Tumor necrosis factor, alpha-induced protein 8- like…: “Crystal structure of TIPE2”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.79). MolNFT v1 #63270 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3F4M
Type: protein
Length: 154 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tumor necrosis factor, alpha-induced protein 8- like protein 2
UniProt: Q6P589
Ligands: CL
Pockets: 1 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 81% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tumor necrosis factor, alpha-induced protein 8- like protein 2	protein	154	81% helix, 0% strand	Q6P589

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	662	0.79	0.83	46	empty

Compared structures

3F4M · Crystal structure of TIPE2 · the same entry in another collection · chain A against A, TM-score 1.00
Q6P589 · AlphaFold monomer V2.0 prediction for tumor necrosis factor alpha- induced protein 8-like… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6P589
Elsewhere: RCSB PDB 3F4M · PDBe 3F4M · UniProt Q6P589

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