MolNFT v1 · #63250 · protein
Crystal structure of uncharacterized protein HP0035 from helicobacter pylori
3F42: “Crystal structure of uncharacterized protein HP0035 from helicobacter pylori”. X-ray diffraction, 1 pocket (best druggability 0.69). MolNFT v1 #63250 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3F42
- Type
- protein
- Length
- 177 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein HP0035
- UniProt
- O24876
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 64% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein HP0035 | protein | 93 | 67% helix, 19% strand | O24876 |
| B | Protein HP0035 | protein | 84 | 61% helix, 21% strand | O24876 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 678 | 0.69 | 0.76 | 39 | empty |
Interfaces
1 interface between chains.
- A–B · 1054 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 3F42 · Crystal structure of uncharacterized protein HP0035 from Helicobacter pylori · the same entry in another collection · chain A against A, TM-score 1.00
- O24876 · AlphaFold monomer V2.0 prediction for nucleoid-associated protein HP_0035 (O24876) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O24876
- Elsewhere: RCSB PDB 3F42 · PDBe 3F42 · UniProt O24876
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