MolNFT v1 · #63000 · protein
Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from listeria monocytogenes
3EWB: “Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from listeria monocytogenes”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #63000 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 3EWB
- Type
- protein
- Length
- 271 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 2-isopropylmalate synthase
- EC
- 2.3.3.13
- UniProt
- Q71Y35
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | 2-isopropylmalate synthase (EC 2.3.3.13) | protein | 271 | 51% helix, 20% strand | Q71Y35 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 159 | 0.58 | 0.83 | 20 | empty |
Modifications
Observed in the structure: 3 modified (engineered).
Compared structures
- 3EWB · Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from… · the same entry in another collection · chain X against X, TM-score 1.00
- Q71Y35 · AlphaFold monomer V2.0 prediction for 2-isopropylmalate synthase (Q71Y35) · a predicted model of the same protein · chain X against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q71Y35
- Elsewhere: RCSB PDB 3EWB · PDBe 3EWB · UniProt Q71Y35
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