MolNFT v1 · #62943 · protein
Crystal structure of muke-MUKF(RESIDUES 292-443)-MUKB(HEAD domain)- atpgammas complex, symmetric dimer
3EUJ · Chromosome partition protein mukb, linker: “Crystal structure of muke-MUKF(RESIDUES 292-443)-MUKB(HEAD domain)- atpgammas complex, symmetric dimer”. X-ray diffraction, 2 ligands (AGS, MG), 11 pockets (best druggability 0.77). MolNFT…
- PDB
- 3EUJ
- Type
- protein
- Length
- 527 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromosome partition protein mukb, linker; Chromosome partition protein mukf
- UniProt
- Q7VL96, Q7VL94
- Ligands
- AGS, MG
- Pockets
- 11 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chromosome partition protein mukb, linker | protein | 437 | 36% helix, 25% strand | Q7VL96 |
| B | Chromosome partition protein mukf | protein | 90 | 50% helix, 10% strand | Q7VL94 |
Ligands and binding sites
- AGS · Phosphothiophosphoric acid-adenylate ester · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.77 | 0.99 | 18 | empty |
| 2 | 178 | 0.57 | 0.81 | 29 | AGS, MG |
| 3 | 96 | 0.51 | 0.83 | 19 | empty |
| 4 | 127 | 0.45 | 0.77 | 18 | empty |
| 5 | 158 | 0.43 | 0.75 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 1298 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 3EUJ · Crystal structure of MukE-MukF(residues 292-443)-MukB(head domain)-ATPgammaS complex… · the same entry in another collection · chain A against A, TM-score 1.00
- Q7VL96 · AlphaFold monomer V2.0 prediction for chromosome partition protein mukb (Q7VL96) · a predicted model of the same protein · chain A against A, TM-score 0.95
- Q7VL94 · AlphaFold monomer V2.0 prediction for chromosome partition protein mukf (Q7VL94) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7VL96
- Every structure of UniProt Q7VL94
- Elsewhere: RCSB PDB 3EUJ · PDBe 3EUJ · UniProt Q7VL96 · UniProt Q7VL94
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