MolNFT v1 · #62550 · protein
Crystal structure of single-stranded DNA-binding protein from streptomyces coelicolor
3EIV · Single-stranded DNA-binding protein 2: “Crystal structure of single-stranded DNA-binding protein from streptomyces coelicolor”. X-ray diffraction, 2 pockets (best druggability 0.64). MolNFT v1 #62550 on GenesisL1: 3D structure…
- PDB
- 3EIV
- Type
- protein
- Length
- 420 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Single-stranded DNA-binding protein 2
- UniProt
- Q9X8U3
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 4 distinct chains · 9% helix, 60% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Single-stranded DNA-binding protein 2 | protein | 98 | 9% helix, 60% strand | Q9X8U3 |
| B | Single-stranded DNA-binding protein 2 | protein | 111 | 9% helix, 59% strand | Q9X8U3 |
| C | Single-stranded DNA-binding protein 2 | protein | 111 | 8% helix, 60% strand | Q9X8U3 |
| D | Single-stranded DNA-binding protein 2 | protein | 100 | 10% helix, 59% strand | Q9X8U3 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 311 | 0.64 | 0.81 | 44 | empty |
| 2 | 328 | 0.61 | 0.79 | 42 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1464 Ų buried · 37 hydrogen bonds · protein-protein
- A–B · 1443 Ų buried · 36 hydrogen bonds · protein-protein
- B–C · 984 Ų buried · 14 hydrogen bonds · protein-protein
- A–D · 881 Ų buried · 15 hydrogen bonds · protein-protein
- B–D · 65 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3EIV · Crystal Structure of Single-stranded DNA-binding protein from Streptomyces coelicolor · the same entry in another collection · chain D against D, TM-score 1.00
- Q9X8U3 · AlphaFold monomer V2.0 prediction for single-stranded DNA-binding protein 2 (Q9X8U3) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X8U3
- Elsewhere: RCSB PDB 3EIV · PDBe 3EIV · UniProt Q9X8U3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.