MolNFT v1 · #62526 · protein
Crystal structure of apo-ll-diaminopimelate aminotransferase from arabidopsis thaliana (no plp)
3EI7: “Crystal structure of apo-ll-diaminopimelate aminotransferase from arabidopsis thaliana (no plp)”. X-ray diffraction, 1 ligand (SO4), 6 pockets (best druggability 0.77). MolNFT v1 #62526 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3EI7
- Type
- protein
- Length
- 821 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ll-diaminopimelate aminotransferase
- EC
- 2.6.1.83
- UniProt
- Q93ZN9
- Ligands
- SO4
- Pockets
- 6 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ll-diaminopimelate aminotransferase (EC 2.6.1.83) | protein | 412 | 45% helix, 14% strand | Q93ZN9 |
| B | Ll-diaminopimelate aminotransferase (EC 2.6.1.83) | protein | 409 | 44% helix, 14% strand | Q93ZN9 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 601 | 0.77 | 0.83 | 82 | SO4 |
| 2 | 68 | 0.74 | 0.98 | 19 | empty |
| 3 | 465 | 0.71 | 0.81 | 65 | empty |
| 4 | 175 | 0.67 | 0.87 | 27 | empty |
| 5 | 189 | 0.67 | 0.86 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 3907 Ų buried · 57 hydrogen bonds · protein-protein
Compared structures
- 3EI7 · Crystal structure of apo-LL-diaminopimelate aminotransferase from Arabidopsis thaliana… · the same entry in another collection · chain A against A, TM-score 1.00
- Q93ZN9 · AlphaFold monomer V2.0 prediction for ll-diaminopimelate aminotransferase, chloroplastic… · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93ZN9
- Elsewhere: RCSB PDB 3EI7 · PDBe 3EI7 · UniProt Q93ZN9
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