MolNFT v1 · #62478 · protein
Crystal structure of a tetr-family transcriptional regulator (AF_1817) from archaeoglobus fulgidus at 2.55 a resolution
3EGQ · Tetr family transcriptional regulator: “Crystal structure of a tetr-family transcriptional regulator (AF_1817) from archaeoglobus fulgidus at 2.55 a…”. X-ray diffraction, 1 pocket (best druggability 0.86). MolNFT v1 #62478 on…
- PDB
- 3EGQ
- Type
- protein
- Length
- 329 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetr family transcriptional regulator
- UniProt
- O28458
- Pockets
- 1 · best druggability 0.86
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetr family transcriptional regulator | protein | 165 | 76% helix, 0% strand | O28458 |
| B | Tetr family transcriptional regulator | protein | 164 | 76% helix, 0% strand | O28458 |
Ligands and binding sites
- PE8 · 3,6,9,12,15,18,21-heptaoxatricosane-1,23-diol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1073 | 0.86 | 0.86 | 73 | PE8 |
Interfaces
1 interface between chains.
- A–B · 1331 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 22 modified (engineered).
Compared structures
- 3EGQ · Crystal structure of a tetr-family transcriptional regulator (af_1817) from archaeoglobus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28458
- Elsewhere: RCSB PDB 3EGQ · PDBe 3EGQ · UniProt O28458
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.