MolNFT v1 · #62459 · protein

Crystal structure of 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase from brucella melitensis biovar abortus 2308

3EG4 · 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N…: “Crystal structure of 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase from brucella melitensis…”. X-ray diffraction, 2 pockets (best druggability 0.49). MolNFT v1…

PDB: 3EG4
Type: protein
Length: 279 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N- succinyltransferase
EC: 2.3.1.117
UniProt: Q8FV25
Pockets: 2 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N- succinyltransferase (EC 2.3.1.117)	protein	279	23% helix, 28% strand	Q8FV25

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	167	0.49	0.77	31	empty
2	61	0.29	0.74	17	empty

Compared structures

3EG4 · Crystal structure of 2,3,4,5-Tetrahydropyridine-2-carboxylate N-Succinyltransferase from… · the same entry in another collection · chain A against A, TM-score 1.00
Q8FV25 · AlphaFold monomer V2.0 prediction for 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8FV25
Elsewhere: RCSB PDB 3EG4 · PDBe 3EG4 · UniProt Q8FV25

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