MolNFT v1 · #62414 · protein

Crystal structure of putative gntr-family transcriptional regulator

3EET: “Crystal structure of putative gntr-family transcriptional regulator”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #62414 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3EET
Type: protein
Length: 481 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative gntr-family transcriptional regulator
UniProt: Q82IF8
Pockets: 3 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative gntr-family transcriptional regulator	protein	245	27% helix, 33% strand	Q82IF8
B	Putative gntr-family transcriptional regulator	protein	236	27% helix, 33% strand	Q82IF8

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.56	0.87	18	empty
2	136	0.54	0.81	24	empty
3	93	0.40	0.77	21	empty

Interfaces

1 interface between chains.

A–B · 189 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 14 modified (engineered).

Compared structures

3EET · Crystal structure of putative GntR-family transcriptional regulator · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q82IF8
Elsewhere: RCSB PDB 3EET · PDBe 3EET · UniProt Q82IF8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.