MolNFT v1 · #62395 · protein

Structure of NS1 effector domain

3EE8 · Non-structural protein 1: “Structure of NS1 effector domain”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #62395 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3EE8
Type: protein
Length: 243 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Non-structural protein 1
UniProt: P03495
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 2 distinct chains · 24% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Non-structural protein 1	protein	122	25% helix, 39% strand	P03495
B	Non-structural protein 1	protein	121	23% helix, 40% strand	P03495

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	249	0.50	0.74	23	empty

Interfaces

1 interface between chains.

A–B · 445 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3EE8 · Structure of NS1 effector domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03495
Elsewhere: RCSB PDB 3EE8 · PDBe 3EE8 · UniProt P03495

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