MolNFT v1 · #62257 · protein

Crystal structure of SARS-cov main protease triple mutant STI/A in space group C2

3EA8 · 3C-like proteinase: “Crystal structure of SARS-cov main protease triple mutant STI/A in space group C2”. X-ray diffraction, 2 pockets (best druggability 0.45). MolNFT v1 #62257 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 3EA8
Type: protein
Length: 306 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3C-like proteinase
EC: 3.4.22.-
UniProt: P0C6U8
Pockets: 2 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	3C-like proteinase (EC 3.4.22.-)	protein	306	25% helix, 29% strand	P0C6U8

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	186	0.45	0.75	28	empty
2	116	0.40	0.75	23	empty

Compared structures

3EA8 · Crystal structure of SARS-CoV main protease triple mutant STI/A in space group C2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0C6U8
Elsewhere: RCSB PDB 3EA8 · PDBe 3EA8 · UniProt P0C6U8

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