MolNFT v1 · #62107 · protein

Crystal structure analysis of FP611

3E5T · Red fluorescent protein EQFP611: “Crystal structure analysis of FP611”. X-ray diffraction, 1 ligand (NRQ), 1 pocket (best druggability 0.75). MolNFT v1 #62107 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3E5T
Type: protein
Length: 228 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Red fluorescent protein EQFP611
UniProt: Q8ISF8
Ligands: NRQ
Pockets: 1 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 55% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Red fluorescent protein EQFP611	protein	228	6% helix, 55% strand	Q8ISF8

Ligands and binding sites

NRQ · {(4Z)-4-(4-hydroxybenzylidene)-2-[3-(methylthio) propanimidoyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.75	0.98	23	NRQ

Modifications

Observed in the structure: 2 cofactor (chromophore).

Compared structures

3E5T · Crystal Structure Analysis of FP611 · the same entry in another collection · chain A against A, TM-score 1.00
Q8ISF8 · AlphaFold monomer V2.0 prediction for red fluorescent protein EQFP611 (Q8ISF8) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8ISF8
Elsewhere: RCSB PDB 3E5T · PDBe 3E5T · UniProt Q8ISF8

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