MolNFT v1 · #61575 · protein

Crystal structure of cpaf S499A mutant

3DPN · Protein CT_858: “Crystal structure of cpaf S499A mutant”. X-ray diffraction, 15 pockets (best druggability 0.82). MolNFT v1 #61575 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3DPN
Type: protein
Length: 1,074 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein CT_858
UniProt: O84866
Pockets: 15 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein CT_858	protein	537	31% helix, 20% strand	O84866

Pockets

15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	741	0.82	0.85	83	empty
2	316	0.78	0.89	44	empty
3	279	0.78	0.90	39	empty
4	411	0.77	0.86	43	empty
5	133	0.70	0.90	27	empty

Interfaces

1 interface between chains.

A–B · 342 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

3DPN · Crystal Structure of cpaf s499a mutant · the same entry in another collection · chain A against A, TM-score 1.00
O84866 · AlphaFold monomer V2.0 prediction for protein CT_858 (O84866) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O84866
Elsewhere: RCSB PDB 3DPN · PDBe 3DPN · UniProt O84866

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.