MolNFT v1 · #61527 · protein
The crystal structure of the protein with unknown function from archaeoglobus fulgidus
3DO8 · Phosphopantetheine adenylyltransferase: “The crystal structure of the protein with unknown function from archaeoglobus fulgidus”. X-ray diffraction, 2 pockets (best druggability 0.73). MolNFT v1 #61527 on GenesisL1: 3D structure…
- PDB
- 3DO8
- Type
- protein
- Length
- 258 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphopantetheine adenylyltransferase
- EC
- 2.7.7.3
- UniProt
- O28077
- Pockets
- 2 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphopantetheine adenylyltransferase (EC 2.7.7.3) | protein | 135 | 38% helix, 19% strand | O28077 |
| B | Phosphopantetheine adenylyltransferase (EC 2.7.7.3) | protein | 123 | 43% helix, 20% strand | O28077 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 240 | 0.73 | 0.88 | 41 | empty |
| 2 | 276 | 0.72 | 0.86 | 38 | empty |
Interfaces
1 interface between chains.
- A–B · 1138 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 3DO8 · The crystal structure of the protein with unknown function from Archaeoglobus fulgidus · the same entry in another collection · chain A against A, TM-score 1.00
- O28077 · AlphaFold monomer V2.0 prediction for phosphopantetheine adenylyltransferase (O28077) · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28077
- Elsewhere: RCSB PDB 3DO8 · PDBe 3DO8 · UniProt O28077
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