MolNFT v1 · #61433 · protein
Crystal structure of a putative S-adenosyl-L-methionine-dependent methyltransferase (MMP1179) from methanococcus maripaludis at 1.15 a resolution
3DLC: “Crystal structure of a putative S-adenosyl-L-methionine-dependent methyltransferase (MMP1179) from…”. X-ray diffraction, 1 ligand (SAM), 2 pockets (best druggability 0.75). MolNFT v1 #61433 on GenesisL1: 3D structure, binding sites…
- PDB
- 3DLC
- Type
- protein
- Length
- 219 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative S-adenosyl-L-methionine-dependent methyltransferase
- UniProt
- Q6LY14
- Ligands
- SAM
- Pockets
- 2 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative S-adenosyl-L-methionine-dependent methyltransferase | protein | 219 | 44% helix, 24% strand | Q6LY14 |
Ligands and binding sites
- SAM · S-adenosylmethionine · ligand · chains A
- GOL · Glycerol · additive · 2 copies · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 451 | 0.75 | 0.84 | 49 | SAM, GOL |
| 2 | 63 | 0.30 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 3DLC · Crystal structure of a putative s-adenosyl-l-methionine-dependent methyltransferase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6LY14
- Elsewhere: RCSB PDB 3DLC · PDBe 3DLC · UniProt Q6LY14
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