MolNFT v1 · #61424 · protein
Crystal structure of the tellurite resistance protein tehb. northeast structural genomics consortium target VFR98 .
3DL3 · Tellurite resistance protein B: “Crystal structure of the tellurite resistance protein tehb. northeast structural genomics consortium target…”. X-ray diffraction, 9 pockets (best druggability 0.77). MolNFT v1 #61424 on GenesisL1: 3D…
- PDB
- 3DL3
- Type
- protein
- Length
- 802 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tellurite resistance protein B
- UniProt
- Q5E3X2
- Pockets
- 9 · best druggability 0.77
Structure
x-ray diffraction · 6 distinct chains · 3% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tellurite resistance protein B | protein | 96 | 4% helix, 50% strand | Q5E3X2 |
| B, D | Tellurite resistance protein B | protein | 96 | 4% helix, 49% strand | Q5E3X2 |
| E, F | Tellurite resistance protein B | protein | 110 | 0% helix, 46% strand | Q5E3X2 |
| G | Tellurite resistance protein B | protein | 94 | 3% helix, 49% strand | Q5E3X2 |
| H | Tellurite resistance protein B | protein | 95 | 0% helix, 49% strand | Q5E3X2 |
| I | Tellurite resistance protein B | protein | 105 | 9% helix, 42% strand | Q5E3X2 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1145 | 0.77 | 0.79 | 94 | empty |
| 2 | 864 | 0.76 | 0.79 | 49 | empty |
| 3 | 851 | 0.74 | 0.78 | 66 | empty |
| 4 | 106 | 0.54 | 0.83 | 25 | empty |
| 5 | 55 | 0.48 | 0.85 | 20 | empty |
Interfaces
16 interfaces between chains.
- B–E · 970 Ų buried · 7 hydrogen bonds · protein-protein
- G–I · 874 Ų buried · 3 hydrogen bonds · protein-protein
- A–E · 367 Ų buried · 3 hydrogen bonds · protein-protein
- B–D · 347 Ų buried · 5 hydrogen bonds · protein-protein
- A–B · 325 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 3DL3 · Crystal structure of the tellurite resistance protein TehB. Northeast Structural Genomics… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5E3X2
- Elsewhere: RCSB PDB 3DL3 · PDBe 3DL3 · UniProt Q5E3X2
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