MolNFT v1 · #6133 · protein
Refined solution structure of 8KDA dynein light chain (DLC8)
1F3C: “Refined solution structure of 8KDA dynein light chain (DLC8)”. Solution nmr, 2 pockets (best druggability 0.35). MolNFT v1 #6133 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1F3C
- Type
- protein
- Length
- 178 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dynein
- UniProt
- P63170
- Pockets
- 2 · best druggability 0.35
Structure
solution nmr · 1 distinct chain · 36% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Dynein | protein | 89 | 36% helix, 24% strand | P63170 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.35 | 0.74 | 18 | empty |
| 2 | 75 | 0.32 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 969 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 1F3C · Refined solution structure of 8KDA dynein light chain (DLC8) · the same entry in another collection · chain A against A, TM-score 1.00
- P63170 · AlphaFold monomer V2.0 prediction for dynein light chain 1, cytoplasmic (P63170) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63170
- Elsewhere: RCSB PDB 1F3C · PDBe 1F3C · UniProt P63170
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