MolNFT v1 · #61103 · protein
Crystal structure of allene oxide synthase
3DBM · Cytochrome P450 74A2: “Crystal structure of allene oxide synthase”. X-ray diffraction, 2 ligands (HEM, HO2), 3 pockets (best druggability 0.84). MolNFT v1 #61103 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3DBM
- Type
- protein
- Length
- 467 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450 74A2
- EC
- 4.2.1.92
- UniProt
- Q40778
- Ligands
- HEM, HO2
- Pockets
- 3 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 74A2 (EC 4.2.1.92) | protein | 467 | 50% helix, 10% strand | Q40778 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
- HO2 · (9E,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1051 | 0.84 | 0.84 | 85 | HEM, HO2 |
| 2 | 143 | 0.40 | 0.73 | 26 | empty |
| 3 | 55 | 0.29 | 0.75 | 15 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q40778
- Elsewhere: RCSB PDB 3DBM · PDBe 3DBM · UniProt Q40778
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.