MolNFT v1 · #61006 · protein
Crystal structure of glmu from mycobacterium tuberculosis in complex with uridine-diphosphate-N-acetylglucosamine
3D8V · Bifunctional protein glmu: “Crystal structure of glmu from mycobacterium tuberculosis in complex with…”. X-ray diffraction, 1 ligand (UD1), 2 pockets (best druggability 0.77). MolNFT v1 #61006 on GenesisL1: 3D structure, binding…
- PDB
- 3D8V
- Type
- protein
- Length
- 478 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bifunctional protein glmu
- EC
- 2.7.7.23, 2.3.1.157
- UniProt
- P96382
- Ligands
- UD1
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 24% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bifunctional protein glmu (EC 2.7.7.23, 2.3.1.157) | protein | 478 | 24% helix, 30% strand | P96382 |
Ligands and binding sites
- UD1 · Uridine-diphosphate-N-acetylglucosamine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 612 | 0.77 | 0.83 | 58 | UD1 |
| 2 | 115 | 0.38 | 0.74 | 17 | empty |
Compared structures
- 3D8V · Crystal structure of GlmU from Mycobacterium tuberculosis in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96382
- Elsewhere: RCSB PDB 3D8V · PDBe 3D8V · UniProt P96382
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.