MolNFT v1 · #60996 · protein

Crystal structure of phosphoglycerate mutase from cryptosporidium parvum, CGD7_4270

3D8H · Glycolytic phosphoglycerate mutase: “Crystal structure of phosphoglycerate mutase from cryptosporidium parvum, CGD7_4270”. X-ray diffraction, 5 pockets (best druggability 0.51). MolNFT v1 #60996 on GenesisL1: 3D structure, binding…

PDB: 3D8H
Type: protein
Length: 464 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycolytic phosphoglycerate mutase
UniProt: Q5CXZ9
Pockets: 5 · best druggability 0.51

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycolytic phosphoglycerate mutase	protein	229	43% helix, 15% strand	Q5CXZ9
B	Glycolytic phosphoglycerate mutase	protein	235	43% helix, 14% strand	Q5CXZ9

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	213	0.51	0.76	26	empty
2	200	0.51	0.77	29	empty
3	177	0.48	0.77	30	empty
4	170	0.47	0.76	26	empty
5	169	0.47	0.76	23	empty

Interfaces

1 interface between chains.

A–B · 794 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

3D8H · Crystal structure of phosphoglycerate mutase from Cryptosporidium parvum, cgd7_4270 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5CXZ9
Elsewhere: RCSB PDB 3D8H · PDBe 3D8H · UniProt Q5CXZ9

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