MolNFT v1 · #60840 · protein
Crystal structure of HIV-1 CRF01_AE in complex with the substrate P1- P6
3D3T · HIV-1 protease: “Crystal structure of HIV-1 CRF01_AE in complex with the substrate P1- P6”. X-ray diffraction. MolNFT v1 #60840 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3D3T
- Type
- protein
- Length
- 206 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HIV-1 protease; P1-P6 substrate peptide
- EC
- 3.4.23.16
- UniProt
- Q90VT5, P12495
Structure
x-ray diffraction · 2 distinct chains · 4% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | HIV-1 protease (EC 3.4.23.16) | protein | 99 | 4% helix, 56% strand | Q90VT5 |
| P | P1-P6 substrate peptide | protein | 8 | 0% helix, 38% strand | P12495 |
Interfaces
3 interfaces between chains.
- A–B · 1835 Ų buried · 28 hydrogen bonds · protein-protein
- B–P · 511 Ų buried · 11 hydrogen bonds · protein-protein
- A–P · 434 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 3D3T · Crystal Structure of HIV-1 CRF01_AE in complex with the substrate p1-p6 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q90VT5
- Every structure of UniProt P12495
- Elsewhere: RCSB PDB 3D3T · PDBe 3D3T · UniProt Q90VT5 · UniProt P12495
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