MolNFT v1 · #6082 · protein
Src SH2 THREF1TRP mutant complexed with the phosphopeptide S(PTR)VNVQN
1F1W · Proto-oncogene tyrosine-protein kinase src: “Src SH2 THREF1TRP mutant complexed with the phosphopeptide S(PTR)VNVQN”. X-ray diffraction. MolNFT v1 #6082 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1F1W
- Type
- protein
- Length
- 111 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proto-oncogene tyrosine-protein kinase src; S(PTR)VNVQN phosphopeptide
- EC
- 2.7.1.112
- UniProt
- P00523
Structure
x-ray diffraction · 2 distinct chains · 14% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proto-oncogene tyrosine-protein kinase src (EC 2.7.1.112) | protein | 104 | 15% helix, 33% strand | P00523 |
| B | S(PTR)VNVQN phosphopeptide | protein | 7 | 0% helix, 0% strand | — |
Interfaces
1 interface between chains.
- A–B · 381 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1F1W · Src SH2 THREF1TRP mutant complexed with the phosphopeptide S(PTR)VNVQN · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00523
- Elsewhere: RCSB PDB 1F1W · PDBe 1F1W · UniProt P00523
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