MolNFT v1 · #60633 · protein
Crystal structure of an uncharacterized protein from methanothermobacter thermautotrophicus
3CXJ: “Crystal structure of an uncharacterized protein from methanothermobacter thermautotrophicus”. X-ray diffraction, 6 pockets (best druggability 0.74). MolNFT v1 #60633 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3CXJ
- Type
- protein
- Length
- 576 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- O27461
- Pockets
- 6 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Uncharacterized protein | protein | 144 | 43% helix, 29% strand | O27461 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1062 | 0.74 | 0.77 | 61 | empty |
| 2 | 470 | 0.58 | 0.73 | 45 | empty |
| 3 | 184 | 0.44 | 0.73 | 25 | empty |
| 4 | 140 | 0.42 | 0.74 | 25 | empty |
| 5 | 116 | 0.37 | 0.73 | 25 | empty |
Interfaces
5 interfaces between chains.
- A–B · 905 Ų buried · 17 hydrogen bonds · protein-protein
- A–D · 896 Ų buried · 16 hydrogen bonds · protein-protein
- B–C · 893 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 889 Ų buried · 16 hydrogen bonds · protein-protein
- B–D · 20 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 modified (engineered).
Compared structures
- 3CXJ · Crystal structure of an uncharacterized protein from Methanothermobacter… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O27461
- Elsewhere: RCSB PDB 3CXJ · PDBe 3CXJ · UniProt O27461
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