MolNFT v1 · #60614 · protein

Crystal structure of cagd from helicobacter pylori pathogenicity island

3CWX · Protein cagd: “Crystal structure of cagd from helicobacter pylori pathogenicity island”. X-ray diffraction, 3 pockets (best druggability 0.63). MolNFT v1 #60614 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3CWX
Type: protein
Length: 375 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein cagd
UniProt: P94837
Pockets: 3 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Protein cagd	protein	125	30% helix, 28% strand	P94837

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	256	0.63	0.81	29	empty
2	154	0.49	0.78	19	empty
3	85	0.39	0.78	16	empty

Interfaces

3 interfaces between chains.

A–B · 981 Å² buried · 12 hydrogen bonds · protein-protein
A–C · 643 Å² buried · 8 hydrogen bonds · protein-protein
B–C · 13 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 9 modified, 4 disulfide (engineered, disulfide).

Compared structures

3CWX · Crystal structure of cagd from helicobacter pylori pathogenicity island · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P94837
Elsewhere: RCSB PDB 3CWX · PDBe 3CWX · UniProt P94837

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