MolNFT v1 · #60521 · protein

Crystal structure of a two component transcriptional regulator arac from clostridium phytofermentans isdg

3CU5 · Two component transcriptional regulator, arac family: “Crystal structure of a two component transcriptional regulator arac from clostridium phytofermentans isdg”. X-ray diffraction, 3 pockets (best druggability 0.59). MolNFT v1…

PDB: 3CU5
Type: protein
Length: 253 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Two component transcriptional regulator, arac family
UniProt: A9KIW7
Pockets: 3 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 41% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Two component transcriptional regulator, arac family	protein	124	41% helix, 19% strand	A9KIW7
B	Two component transcriptional regulator, arac family	protein	129	41% helix, 22% strand	A9KIW7

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	329	0.59	0.77	34	empty
2	84	0.44	0.80	17	empty
3	91	0.44	0.79	18	empty

Interfaces

1 interface between chains.

A–B · 621 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

3CU5 · Crystal structure of a two component transcriptional regulator AraC from Clostridium… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A9KIW7
Elsewhere: RCSB PDB 3CU5 · PDBe 3CU5 · UniProt A9KIW7

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