MolNFT v1 · #6043 · protein

Monomeric structure of the human EPHB2 SAM (sterile alpha motif) domain

1F0M · Ephrin type-B receptor 2: “Monomeric structure of the human EPHB2 SAM (sterile alpha motif) domain”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #6043 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1F0M
Type: protein
Length: 71 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ephrin type-B receptor 2
UniProt: P29323
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ephrin type-B receptor 2	protein	71	63% helix, 0% strand	P29323

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.33	0.77	12	empty

Compared structures

1F0M · Monomeric structure of the human EPHB2 SAM (sterile alpha motif) domain · the same entry in another collection · chain A against A, TM-score 1.00
P29323 · AlphaFold monomer V2.0 prediction for ephrin type-B receptor 2 (P29323) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29323
Elsewhere: RCSB PDB 1F0M · PDBe 1F0M · UniProt P29323

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