MolNFT v1 · #60356 · protein

Crystal structure of a thermostable serine protease AL20 from extremophilic microoganism

3CP7 · Alkaline serine protease AL20: “Crystal structure of a thermostable serine protease AL20 from extremophilic microoganism”. X-ray diffraction, 2 pockets (best druggability 0.36). MolNFT v1 #60356 on GenesisL1: 3D structure, binding…

PDB: 3CP7
Type: protein
Length: 432 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alkaline serine protease AL20
EC: 3.4.21.1
Pockets: 2 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Alkaline serine protease AL20 (EC 3.4.21.1)	protein	216	13% helix, 39% strand	—

Ligands and binding sites

FMT · Formic acid · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.36	0.77	16	empty
2	89	0.34	0.74	26	FMT

Interfaces

1 interface between chains.

A–B · 942 Å² buried · 25 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

3CP7 · Crystal structure of a thermostable serine protease AL20 from extremophilic microoganism · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3CP7 · PDBe 3CP7

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