MolNFT v1 · #59887 · protein
Functional and structural characterization of a cationdependent O- methyltransferase from the cyanobacterium synechocystis sp. strain pcc 6803
3CBG · O-methyltransferase: “Functional and structural characterization of a cationdependent O- methyltransferase from the cyanobacterium…”. X-ray diffraction, 4 ligands (SAH, FER, 4FE), 1 pocket (best druggability 0.51). MolNFT v1 #59887…
- PDB
- 3CBG
- Type
- protein
- Length
- 218 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- O-methyltransferase
- EC
- 2.1.1.-
- UniProt
- Q55813
- Ligands
- SAH, FER, 4FE, MG
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | O-methyltransferase (EC 2.1.1.-) | protein | 218 | 46% helix, 21% strand | Q55813 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- FER · 3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid · ligand · chains A
- 4FE · (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.51 | 0.79 | 29 | SAH, FER, 4FE |
Compared structures
- 3CBG · Functional and Structural Characterization of a Cationdependent O-Methyltransferase from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q55813
- Elsewhere: RCSB PDB 3CBG · PDBe 3CBG · UniProt Q55813
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