MolNFT v1 · #59738 · protein

Structure of cehc variant resa

3C73 · Thiol-disulfide oxidoreductase resa: “Structure of cehc variant resa”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.52). MolNFT v1 #59738 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3C73
Type: protein
Length: 274 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thiol-disulfide oxidoreductase resa
UniProt: P35160
Ligands: SO4
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 36% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thiol-disulfide oxidoreductase resa	protein	136	37% helix, 26% strand	P35160
B	Thiol-disulfide oxidoreductase resa	protein	138	36% helix, 28% strand	P35160

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	164	0.52	0.79	34	empty

Interfaces

1 interface between chains.

A–B · 432 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3C73 · Structure of CEHC variant ResA · the same entry in another collection · chain A against A, TM-score 1.00
P35160 · AlphaFold monomer V2.0 prediction for thiol-disulfide oxidoreductase resa (P35160) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35160
Elsewhere: RCSB PDB 3C73 · PDBe 3C73 · UniProt P35160

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