MolNFT v1 · #59676 · protein
Crystal structure of the mycobacterium tuberculosis hypoxic response regulator dosr C-terminal domain crystal form II
3C57 · Two component transcriptional regulatory protein devr: “Crystal structure of the mycobacterium tuberculosis hypoxic response regulator dosr C-terminal domain crystal…”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1…
- PDB
- 3C57
- Type
- protein
- Length
- 100 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Two component transcriptional regulatory protein devr
- UniProt
- P95193
- Pockets
- 1 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 68% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Two component transcriptional regulatory protein devr | protein | 51 | 67% helix, 0% strand | P95193 |
| B | Two component transcriptional regulatory protein devr | protein | 49 | 69% helix, 0% strand | P95193 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 108 | 0.41 | 0.77 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 697 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 3C57 · Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P95193
- Elsewhere: RCSB PDB 3C57 · PDBe 3C57 · UniProt P95193
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