MolNFT v1 · #59333 · protein

Crystal structure of lola superfamily protein NE2245 from nitrosomonas europaea

3BUU · Uncharacterized lola superfamily protein NE2245: “Crystal structure of lola superfamily protein NE2245 from nitrosomonas europaea”. X-ray diffraction, 8 pockets (best druggability 0.78). MolNFT v1 #59333 on GenesisL1: 3D structure…

PDB: 3BUU
Type: protein
Length: 444 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized lola superfamily protein NE2245
UniProt: Q82SR2
Pockets: 8 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 10% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized lola superfamily protein NE2245	protein	224	10% helix, 53% strand	Q82SR2
B	Uncharacterized lola superfamily protein NE2245	protein	220	10% helix, 53% strand	Q82SR2

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	103	0.78	0.98	25	empty
2	86	0.77	0.98	23	empty
3	228	0.59	0.80	29	empty
4	92	0.44	0.79	20	empty
5	65	0.42	0.81	18	empty

Interfaces

1 interface between chains.

A–B · 243 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

3BUU · Crystal structure of LolA superfamily protein NE2245 from Nitrosomonas europaea · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q82SR2
Elsewhere: RCSB PDB 3BUU · PDBe 3BUU · UniProt Q82SR2

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