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MolNFT v1 · #59250 · protein + RNA

Crystal structure of human PUMILIO1 in complex with cyclinb reverse RNA

3BSB · 5'-R(*UP*UP*UP*AP*AP*UP*GP*UP*U)-3': “Crystal structure of human PUMILIO1 in complex with cyclinb reverse RNA”. X-ray diffraction. MolNFT v1 #59250 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3BSB
Type
protein + RNA
Length
690 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-R(*UP*UP*UP*AP*AP*UP*GP*UP*U)-3'; Pumilio homolog 1
UniProt
Q14671

Structure

x-ray diffraction · 3 distinct chains · 72% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
C5'-R(*UP*UP*UP*AP*AP*UP*GP*UP*U)-3'rna9——
APumilio homolog 1protein34072% helix, 1% strandQ14671
BPumilio homolog 1protein34171% helix, 1% strandQ14671

Interfaces

2 interfaces between chains.

  • C–B · 1376 Ų buried · 45 hydrogen bonds · protein-nucleic
  • A–B · 702 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 3BSB · Crystal Structure of Human Pumilio1 in Complex with CyclinB reverse RNA · the same entry in another collection · chain C against C, TM-score 1.00
  • Q14671 · AlphaFold monomer V2.0 prediction for pumilio homolog 1 (Q14671) · a predicted model of the same protein · chain A against A, TM-score 0.99

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