MolNFT v1 · #59175 · protein

Crystal structure of AD35 fiber knob

3BQ4: “Crystal structure of AD35 fiber knob”. X-ray diffraction, 20 pockets (best druggability 0.84). MolNFT v1 #59175 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3BQ4
Type: protein
Length: 1,152 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fiber
UniProt: Q7T925
Pockets: 20 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, D, E, F, G	Fiber	protein	192	4% helix, 37% strand	Q7T925

Pockets

20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	332	0.84	0.93	39	empty
2	328	0.83	0.93	40	empty
3	213	0.74	0.90	38	empty
4	207	0.73	0.88	42	empty
5	202	0.71	0.88	34	empty

Interfaces

7 interfaces between chains.

E–G · 1008 Å² buried · 11 hydrogen bonds · protein-protein
A–D · 1001 Å² buried · 11 hydrogen bonds · protein-protein
F–G · 967 Å² buried · 9 hydrogen bonds · protein-protein
E–F · 966 Å² buried · 9 hydrogen bonds · protein-protein
A–B · 961 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

3BQ4 · Crystal Structure of Ad35 fiber knob · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7T925
Elsewhere: RCSB PDB 3BQ4 · PDBe 3BQ4 · UniProt Q7T925

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