MolNFT v1 · #59023 · protein
Crystal structure of staphylococcus aureus 5'- METHYLTHIOADENOSINE/S-adenosylhomocysteine nucleosidase in complex with formycin a
3BL6 · 5'-methylthioadenosine NUCLEOSIDASE/S- adenosylhomocysteine…: “Crystal structure of staphylococcus aureus 5'- METHYLTHIOADENOSINE/S-adenosylhomocysteine nucleosidase in…”. X-ray diffraction, 1 ligand (FMC), 1 pocket (best…
- PDB
- 3BL6
- Type
- protein
- Length
- 230 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-methylthioadenosine NUCLEOSIDASE/S- adenosylhomocysteine nucleosidase
- EC
- 3.2.2.9, 3.2.2.16
- UniProt
- Q99TQ0
- Ligands
- FMC
- Pockets
- 1 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5'-methylthioadenosine NUCLEOSIDASE/S- adenosylhomocysteine nucleosidase (EC 3.2.2.9, 3.2.2.16) | protein | 230 | 37% helix, 30% strand | Q99TQ0 |
Ligands and binding sites
- FMC · (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.64 | 0.91 | 19 | FMC |
Compared structures
- 3BL6 · Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine… · the same entry in another collection · chain A against A, TM-score 1.00
- Q99TQ0 · AlphaFold monomer V2.0 prediction for 5'-METHYLTHIOADENOSINE/S-adenosylhomocysteine… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99TQ0
- Elsewhere: RCSB PDB 3BL6 · PDBe 3BL6 · UniProt Q99TQ0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.