MolNFT v1 · #5888 · protein
Crystal structure analysis of the sensor domain of RMFIXL(FERROUS form)
1EW0: “Crystal structure analysis of the sensor domain of RMFIXL(FERROUS form)”. X-ray diffraction, 1 ligand (HEM), 1 pocket (best druggability 0.79). MolNFT v1 #5888 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1EW0
- Type
- protein
- Length
- 130 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fixl
- EC
- 2.7.3.-
- UniProt
- P10955
- Ligands
- HEM
- Pockets
- 1 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fixl (EC 2.7.3.-) | protein | 130 | 35% helix, 32% strand | P10955 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 247 | 0.79 | 0.91 | 29 | HEM |
Compared structures
- 1EW0 · Crystal structure analysis of the sensor domain of RMFIXL(FERROUS form) · the same entry in another collection · chain A against A, TM-score 1.00
- P10955 · AlphaFold monomer V2.0 prediction for sensor protein fixl (P10955) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10955
- Elsewhere: RCSB PDB 1EW0 · PDBe 1EW0 · UniProt P10955
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