MolNFT v1 · #58709 · protein
Crystal structure of a regulatory protein of laci family from chloroflexus aggregans
3BBL: “Crystal structure of a regulatory protein of laci family from chloroflexus aggregans”. X-ray diffraction, 2 pockets (best druggability 0.77). MolNFT v1 #58709 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3BBL
- Type
- protein
- Length
- 281 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein of laci family
- UniProt
- A0H3S5
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulatory protein of laci family | protein | 281 | 38% helix, 19% strand | A0H3S5 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 615 | 0.77 | 0.83 | 49 | empty |
| 2 | 102 | 0.48 | 0.80 | 19 | EDO |
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 3BBL · Crystal structure of a regulatory protein of LacI family from Chloroflexus aggregans · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0H3S5
- Elsewhere: RCSB PDB 3BBL · PDBe 3BBL · UniProt A0H3S5
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