MolNFT v1 · #58568 · protein
Crystal structure of yeast SEC14 homolog SFH1 in complex with phosphatidylinositol
3B7N · Uncharacterized protein YKL091C: “Crystal structure of yeast SEC14 homolog SFH1 in complex with phosphatidylinositol”. X-ray diffraction, 2 ligands (B7N, PO4), 2 pockets (best druggability 0.85). MolNFT v1 #58568 on GenesisL1: 3D…
- PDB
- 3B7N
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein YKL091C
- UniProt
- P33324
- Ligands
- B7N, PO4
- Pockets
- 2 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein YKL091C | protein | 307 | 48% helix, 11% strand | P33324 |
Ligands and binding sites
- B7N · (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate · ligand · chains A
- PO4 · Phosphate ion · ion · 2 copies · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 894 | 0.85 | 0.87 | 91 | B7N |
| 2 | 180 | 0.59 | 0.82 | 22 | empty |
Compared structures
- 3B7N · Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylinositol · the same entry in another collection · chain A against A, TM-score 1.00
- P33324 · AlphaFold monomer V2.0 prediction for cral-trio domain-containing protein YKL091C (P33324) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33324
- Elsewhere: RCSB PDB 3B7N · PDBe 3B7N · UniProt P33324
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