MolNFT v1 · #58449 · protein
Periplasmic sensor domain of chemotaxis protein GSU0935
3B42 · Methyl-accepting chemotaxis protein, putative: “Periplasmic sensor domain of chemotaxis protein GSU0935”. X-ray diffraction, 1 ligand (HEM), 4 pockets (best druggability 0.69). MolNFT v1 #58449 on GenesisL1: 3D structure, binding…
- PDB
- 3B42
- Type
- protein
- Length
- 255 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methyl-accepting chemotaxis protein, putative
- UniProt
- Q74EM7
- Ligands
- HEM
- Pockets
- 4 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methyl-accepting chemotaxis protein, putative | protein | 126 | 40% helix, 31% strand | Q74EM7 |
| B | Methyl-accepting chemotaxis protein, putative | protein | 129 | 40% helix, 28% strand | Q74EM7 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.69 | 0.97 | 19 | empty |
| 2 | 130 | 0.61 | 0.86 | 20 | empty |
| 3 | 133 | 0.53 | 0.81 | 23 | HEM |
| 4 | 120 | 0.47 | 0.79 | 26 | HEM |
Interfaces
1 interface between chains.
- A–B · 2591 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 cofactor (heme attachment).
Compared structures
- 3B42 · Periplasmic sensor domain of chemotaxis protein GSU0935 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q74EM7
- Elsewhere: RCSB PDB 3B42 · PDBe 3B42 · UniProt Q74EM7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.