MolNFT v1 · #58072 · protein

Crystal structure of plp-bound ll-diaminopimelate aminotransferase from chlamydia trachomatis

3ASB: “Crystal structure of plp-bound ll-diaminopimelate aminotransferase from chlamydia trachomatis”. X-ray diffraction, 4 pockets (best druggability 0.48). MolNFT v1 #58072 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3ASB
Type: protein
Length: 364 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ll-diaminopimelate aminotransferase
EC: 2.6.1.83
UniProt: O84395
Pockets: 4 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ll-diaminopimelate aminotransferase (EC 2.6.1.83)	protein	364	42% helix, 16% strand	O84395

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	119	0.48	0.79	19	empty
2	165	0.45	0.75	24	empty
3	123	0.42	0.75	16	empty
4	64	0.29	0.74	15	empty

Modifications

Observed in the structure: 1 modified (cofactor).

Compared structures

3ASB · Crystal structure of PLP-bound LL-diaminopimelate aminotransferase from Chlamydia… · the same entry in another collection · chain A against A, TM-score 1.00
O84395 · AlphaFold monomer V2.0 prediction for ll-diaminopimelate aminotransferase (O84395) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O84395
Elsewhere: RCSB PDB 3ASB · PDBe 3ASB · UniProt O84395

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