MolNFT v1 · #58071 · protein

Crystal structure of apo-ll-diaminopimelate aminotransferase from chlamydia trachomatis

3ASA: “Crystal structure of apo-ll-diaminopimelate aminotransferase from chlamydia trachomatis”. X-ray diffraction, 4 pockets (best druggability 0.68). MolNFT v1 #58071 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3ASA
Type: protein
Length: 388 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ll-diaminopimelate aminotransferase
EC: 2.6.1.83
UniProt: O84395
Pockets: 4 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ll-diaminopimelate aminotransferase (EC 2.6.1.83)	protein	388	43% helix, 15% strand	O84395

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	647	0.68	0.77	61	empty
2	123	0.44	0.77	23	empty
3	127	0.42	0.76	16	empty
4	66	0.30	0.74	15	empty

Compared structures

3ASA · Crystal structure of apo-LL-diaminopimelate aminotransferase from Chlamydia trachomatis · the same entry in another collection · chain A against A, TM-score 1.00
O84395 · AlphaFold monomer V2.0 prediction for ll-diaminopimelate aminotransferase (O84395) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O84395
Elsewhere: RCSB PDB 3ASA · PDBe 3ASA · UniProt O84395

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