MolNFT v1 · #58025 · protein

Crystal structure of secdf, a translocon-associated membrane protein, from thermus thrmophilus

3AQP · Probable secdf protein-export membrane protein: “Crystal structure of secdf, a translocon-associated membrane protein, from thermus thrmophilus”. X-ray diffraction, 20 pockets (best druggability 0.84). MolNFT v1 #58025 on GenesisL1…

PDB: 3AQP
Type: protein
Length: 1,438 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable secdf protein-export membrane protein
UniProt: Q5SKE6
Pockets: 20 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Probable secdf protein-export membrane protein	protein	719	62% helix, 12% strand	Q5SKE6

Pockets

20 pockets found on a 1 Å grid, 17 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1092	0.84	0.85	133	empty
2	1173	0.82	0.83	132	empty
3	450	0.79	0.86	54	empty
4	459	0.77	0.85	56	empty
5	90	0.76	0.97	30	empty

Interfaces

1 interface between chains.

A–B · 140 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

3AQP · Crystal structure of SecDF, a translocon-associated membrane protein, from Thermus… · the same entry in another collection · chain A against A, TM-score 1.00
Q5SKE6 · AlphaFold monomer V2.0 prediction for protein translocase subunit secdf (Q5SKE6) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SKE6
Elsewhere: RCSB PDB 3AQP · PDBe 3AQP · UniProt Q5SKE6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.