MolNFT v1 · #57954 · protein
Crystal structure of the C-terminal domain of sequence-specific ribonuclease
3AO9 · Colicin-E5: “Crystal structure of the C-terminal domain of sequence-specific ribonuclease”. X-ray diffraction, 1 ligand (CD), 2 pockets (best druggability 0.65). MolNFT v1 #57954 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 3AO9
- Type
- protein
- Length
- 183 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Colicin-E5
- EC
- 3.1.-.-
- UniProt
- P18000
- Ligands
- CD
- Pockets
- 2 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 22% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Colicin-E5 (EC 3.1.-.-) | protein | 97 | 24% helix, 34% strand | P18000 |
| B | Colicin-E5 (EC 3.1.-.-) | protein | 86 | 21% helix, 36% strand | P18000 |
Ligands and binding sites
- CD · Cadmium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.65 | 0.95 | 26 | empty |
| 2 | 147 | 0.50 | 0.79 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 606 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18000
- Elsewhere: RCSB PDB 3AO9 · PDBe 3AO9 · UniProt P18000
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