MolNFT v1 · #57883 · protein

Crystal structure of nanos

3ALR · Nanos protein: “Crystal structure of nanos”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.57). MolNFT v1 #57883 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3ALR
Type: protein
Length: 250 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nanos protein
UniProt: Q4QRE8
Ligands: ZN
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 4 distinct chains · 31% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nanos protein	protein	63	35% helix, 5% strand	Q4QRE8
B	Nanos protein	protein	65	28% helix, 5% strand	Q4QRE8
C	Nanos protein	protein	67	27% helix, 4% strand	Q4QRE8
D	Nanos protein	protein	55	35% helix, 5% strand	Q4QRE8

Ligands and binding sites

ZN · Zinc ion · metal · 10 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	399	0.57	0.74	49	empty

Interfaces

3 interfaces between chains.

A–B · 792 Å² buried · 5 hydrogen bonds · protein-protein
C–D · 779 Å² buried · 5 hydrogen bonds · protein-protein
A–D · 562 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3ALR · Crystal structure of Nanos · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4QRE8
Elsewhere: RCSB PDB 3ALR · PDBe 3ALR · UniProt Q4QRE8

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