MolNFT v1 · #57850 · protein

X-ray structure of ifabp from human and rat with bound fluorescent fatty acid analogue

3AKN · Fatty acid-binding protein, intestinal: “X-ray structure of ifabp from human and rat with bound fluorescent fatty acid analogue”. X-ray diffraction, 1 ligand (11D), 1 pocket (best druggability 0.82). MolNFT v1 #57850 on GenesisL1…

PDB: 3AKN
Type: protein
Length: 130 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fatty acid-binding protein, intestinal
UniProt: P02693
Ligands: 11D
Pockets: 1 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 58% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fatty acid-binding protein, intestinal	protein	130	11% helix, 58% strand	P02693

Ligands and binding sites

11D · 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino) undecanoic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	312	0.82	0.92	33	11D

Compared structures

3AKN · X-ray structure of iFABP from human and rat with bound fluorescent fatty acid analogue · the same entry in another collection · chain A against A, TM-score 1.00
P02693 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein, intestinal (P02693) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02693
Elsewhere: RCSB PDB 3AKN · PDBe 3AKN · UniProt P02693

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