MolNFT v1 · #57626 · protein

Crystal structure of the rabbit L-gulonate 3-dehydrogenase

3ADO · Lambda-crystallin: “Crystal structure of the rabbit L-gulonate 3-dehydrogenase”. X-ray diffraction, 5 pockets (best druggability 0.55). MolNFT v1 #57626 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3ADO
Type: protein
Length: 310 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lambda-crystallin
EC: 1.1.1.45
UniProt: P14755
Pockets: 5 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 55% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lambda-crystallin (EC 1.1.1.45)	protein	310	55% helix, 13% strand	P14755

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	381	0.55	0.73	35	empty
2	139	0.51	0.79	19	empty
3	60	0.35	0.77	11	empty
4	57	0.27	0.72	11	empty
5	51	0.24	0.72	10	empty

Compared structures

3ADO · Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
P14755 · AlphaFold monomer V2.0 prediction for lambda-crystallin (P14755) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14755
Elsewhere: RCSB PDB 3ADO · PDBe 3ADO · UniProt P14755

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