MolNFT v1 · #57474 · protein

Crystal structure of the TIAM1 phccex domain

3A8N · T-lymphoma invasion and metastasis-inducing protein 1: “Crystal structure of the TIAM1 phccex domain”. X-ray diffraction, 1 pocket (best druggability 0.78). MolNFT v1 #57474 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3A8N
Type: protein
Length: 230 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: T-lymphoma invasion and metastasis-inducing protein 1
UniProt: Q60610
Pockets: 1 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	T-lymphoma invasion and metastasis-inducing protein 1	protein	230	41% helix, 16% strand	Q60610

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1038	0.78	0.80	122	empty

Compared structures

3A8N · Crystal structure of the Tiam1 PHCCEx domain · the same entry in another collection · chain A against A, TM-score 1.00
Q60610 · AlphaFold monomer V2.0 prediction for T-lymphoma invasion and metastasis-inducing protein… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q60610
Elsewhere: RCSB PDB 3A8N · PDBe 3A8N · UniProt Q60610

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