MolNFT v1 · #57287 · protein

E. COLI gsp amidase CYS59 sulfenic acid

3A2Z · Bifunctional glutathionylspermidine SYNTHETASE/AMIDASE: “E. COLI gsp amidase CYS59 sulfenic acid”. X-ray diffraction, 1 pocket (best druggability 0.44). MolNFT v1 #57287 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3A2Z
Type: protein
Length: 190 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bifunctional glutathionylspermidine SYNTHETASE/AMIDASE
EC: 6.3.1.8, 3.5.1.78
UniProt: P0AES0
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Bifunctional glutathionylspermidine SYNTHETASE/AMIDASE (EC 6.3.1.8, 3.5.1.78)	protein	190	16% helix, 35% strand	P0AES0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.44	0.78	23	empty

Compared structures

3A2Z · E. coli Gsp amidase Cys59 sulfenic acid · the same entry in another collection · chain A against A, TM-score 1.00
P0AES0 · AlphaFold monomer V2.0 prediction for bifunctional glutathionylspermidine… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AES0
Elsewhere: RCSB PDB 3A2Z · PDBe 3A2Z · UniProt P0AES0

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