MolNFT v1 · #57238 · protein

High-resolution crystal structure of RNA polymerase PB1-PB2 subunits from influenza a virus

3A1G · RNA-directed RNA polymerase catalytic subunit: “High-resolution crystal structure of RNA polymerase PB1-PB2 subunits from influenza a virus”. X-ray diffraction. MolNFT v1 #57238 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 3A1G
Type: protein
Length: 222 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-directed RNA polymerase catalytic subunit; Polymerase basic protein 2
EC: 2.7.7.48
UniProt: P03431, P03428

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48)	protein	73	70% helix, 1% strand	P03431
B, D	Polymerase basic protein 2	protein	38	74% helix, 3% strand	P03428

Interfaces

6 interfaces between chains.

A–B · 1663 Å² buried · 20 hydrogen bonds · protein-protein
C–D · 1555 Å² buried · 15 hydrogen bonds · protein-protein
A–C · 265 Å² buried · 4 hydrogen bonds · protein-protein
A–D · 258 Å² buried · 7 hydrogen bonds · protein-protein
B–C · 247 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 14 modified (engineered).

Compared structures

3A1G · High-Resolution Crystal Structure of RNA polymerase PB1-PB2 subunits from Influenza A… · the same entry in another collection · chain C against C, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03431
Every structure of UniProt P03428
Elsewhere: RCSB PDB 3A1G · PDBe 3A1G · UniProt P03431 · UniProt P03428

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