MolNFT v1 · #5711 · protein

Exo-B-(1,3)-glucanase from candida albicans in complex with castanospermine at 1.85 a

1EQC · Exo-(B)-(1,3)-glucanase: “Exo-B-(1,3)-glucanase from candida albicans in complex with castanospermine at 1.85 a”. X-ray diffraction, 1 ligand (CTS), 1 pocket (best druggability 0.65). MolNFT v1 #5711 on GenesisL1: 3D structure…

PDB: 1EQC
Type: protein
Length: 394 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Exo-(B)-(1,3)-glucanase
EC: 3.2.1.58
UniProt: P29717
Ligands: CTS
Pockets: 1 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exo-(B)-(1,3)-glucanase (EC 3.2.1.58)	protein	394	39% helix, 12% strand	P29717

Ligands and binding sites

CTS · Castanospermine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	354	0.65	0.80	41	CTS

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1EQC · Exo-B-(1,3)-glucanase from candida albicans in complex with castanospermine at 1.85 a · the same entry in another collection · chain A against A, TM-score 1.00
P29717 · AlphaFold monomer V2.0 prediction for glucan 1,3-beta-glucosidase (P29717) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29717
Elsewhere: RCSB PDB 1EQC · PDBe 1EQC · UniProt P29717

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