MolNFT v1 · #57052 · protein
A. fulgidus lipase with fatty acid fragment and chloride
2ZYS · Lipase, putative: “A. fulgidus lipase with fatty acid fragment and chloride”. X-ray diffraction, 1 ligand (CL), 7 pockets (best druggability 0.81). MolNFT v1 #57052 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2ZYS
- Type
- protein
- Length
- 460 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipase, putative
- EC
- 3.1.1.3
- UniProt
- O28511
- Ligands
- CL
- Pockets
- 7 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lipase, putative (EC 3.1.1.3) | protein | 460 | 25% helix, 28% strand | O28511 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 169 | 0.81 | 0.96 | 40 | PG4 |
| 2 | 51 | 0.65 | 0.95 | 18 | empty |
| 3 | 197 | 0.47 | 0.75 | 25 | empty |
| 4 | 69 | 0.42 | 0.80 | 15 | empty |
| 5 | 77 | 0.35 | 0.76 | 19 | empty |
Compared structures
- 2ZYS · A. Fulgidus lipase with fatty acid fragment and chloride · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28511
- Elsewhere: RCSB PDB 2ZYS · PDBe 2ZYS · UniProt O28511
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